Berberine ursodeoxycholate
CAS No. 1868138-66-2
Berberine ursodeoxycholate ( —— )
产品货号. M36122 CAS No. 1868138-66-2
Berberine ursodeoxycholate (HTD1801) 是 Berberine 和 Ursodeoxycholic acid 的一种离子盐,是一种口服有效的降血脂剂 (hypolipidemic agent)。Berberine ursodeoxycholate 能显著降低肝脏脂肪含量。Berberine ursodeoxycholate 具有广泛的代谢活性。Berberine ursodeoxycholate 可用于高脂血症、非酒精性脂肪性肝炎 (NASH) 和糖尿病的研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ¥413 | 有现货 |
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| 5MG | ¥589 | 有现货 |
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| 10MG | ¥953 | 有现货 |
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| 25MG | ¥1853 | 有现货 |
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| 50MG | ¥2956 | 有现货 |
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| 100MG | ¥4353 | 有现货 |
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| 500MG | ¥9104 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Berberine ursodeoxycholate
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Berberine ursodeoxycholate (HTD1801) 是 Berberine 和 Ursodeoxycholic acid 的一种离子盐,是一种口服有效的降血脂剂 (hypolipidemic agent)。Berberine ursodeoxycholate 能显著降低肝脏脂肪含量。Berberine ursodeoxycholate 具有广泛的代谢活性。Berberine ursodeoxycholate 可用于高脂血症、非酒精性脂肪性肝炎 (NASH) 和糖尿病的研究。
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产品描述Berberine ursodeoxycholate (HTD1801), an ionic salt of Berberine and Ursodeoxycholic acid, is an orally active and potent hypolipidemic agent. Berberine ursodeoxycholate shows significantly great reduction in liver fat content. Berberine ursodeoxycholate has a broad spectrum of metabolic activity. Berberine ursodeoxycholate can be used for the research of hyperlipidemia, non-alcoholic steatohepatitis (NASH) and diabetes.
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体外实验——
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体内实验Berberine ursodeoxycholate shows significant reductions in HbA1c (hemoglobin A1c) levels, mean HbA1c levels decreases by 0.6%.Berberine ursodeoxycholate is ingested in the form of a salt and it is thought that the salt promptly dissociates within the gastrointestinal tract and that Berberine and Ursodeoxycholic acid are differentially absorbed.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number1868138-66-2
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分子量217.69
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分子式C6H8CuN3O2
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO 中的溶解度 : 5 mg/mL (6.87 mM; 超声助溶 (<60°C)
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SMILESCOc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC.[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC([O-])=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Harrison SA, et al. A phase 2, proof of concept, randomised controlled trial of berberine ursodeoxycholate in patients with presumed non-alcoholic steatohepatitis and type 2 diabetes. Nat Commun. 2021 Sep 17;12(1):5503.?
产品手册
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